The STK11 gene homepage
| General information |
| Gene symbol |
STK11 |
| Gene name |
serine/threonine kinase 11 |
| Chromosome |
19 |
| Chromosomal band |
p13.3 |
| Imprinted |
- |
| Genomic reference |
NG_007460.1 |
| Transcript reference |
NM_000455.4 |
| Associated with diseases |
WD |
| Citation reference(s) |
Pan M et al, 2011
Zhang T et al, 2010 |
| Refseq URL |
Coding DNA reference sequence |
| Curators (0) |
- |
| Total number of public variants reported |
536 |
| Unique public DNA variants reported |
355 |
| Individuals with public variants |
0 |
| Hidden variants |
- |
| Notes |
This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Also known as: PJS; LKB1; hLKB1 |
| Date created |
May 04, 2011 |
Active transcripts
| Copyright & disclaimer |
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