The MET gene homepage
| General information |
| Gene symbol |
MET |
| Gene name |
met proto-oncogene (hepatocyte growth factor receptor) |
| Chromosome |
7 |
| Chromosomal band |
q31 |
| Imprinted |
- |
| Genomic reference |
NG_008996.1 |
| Transcript reference |
NM_001127500.1 |
| Associated with diseases |
WD |
| Citation reference(s) |
Pan M et al, 2011
Zhang T et al, 2010 |
| Refseq URL |
Coding DNA reference sequence |
| Curators (0) |
- |
| Total number of public variants reported |
122 |
| Unique public DNA variants reported |
104 |
| Individuals with public variants |
0 |
| Hidden variants |
- |
| Notes |
The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Also known as: HGFR; AUTS9; RCCP2; c-Met |
| Date created |
April 21, 2013 |
Active transcripts
| Copyright & disclaimer |
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