The CDC73 gene homepage

General information
Gene symbol CDC73
Gene name cell division cycle 73
Chromosome 1
Chromosomal band q25
Imprinted -
Genomic reference NG_012691.1
Transcript reference NM_024529.4
Associated with diseases WD
Citation reference(s) Pan M et al, 2011
Zhang T et al, 2010
Refseq URL Coding DNA reference sequence
Curators (0) -
Total number of public variants reported 125
Unique public DNA variants reported 89
Individuals with public variants 0
Hidden variants -
Notes This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]
Also known as: HYX; HPTJT; HRPT2; C1orf28
Date created April 15, 2013

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage URL http://www.genomed.org/lovd3/genes/CDC73
HGNC 16783
Entrez Gene 79577
PubMed articles CDC73
OMIM - Gene 607393
OMIM - Diseases WD (wilson disease)
HGMD CDC73
GeneCards CDC73
GeneTests CDC73


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00000034 1 cell division cycle 73 NM_024529.4 - 125


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